| Titre de série : |
aspects fondamentaux et appliqués |
| Titre : |
From torpedo electric organ to human brain : fundamental and applied aspects |
| Titre original : |
De lorgane électrique de torpille au cerveau humaine |
| Type de document : |
texte imprimé |
| Auteurs : |
Jean Massoulié, Auteur |
| Editeur : |
Elsevier |
| Année de publication : |
1998 |
| Importance : |
523 p. |
| Format : |
28 cm |
| ISBN/ISSN/EAN : |
978-2-84299-065-7 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
573 Les différents systèmes physiologiques des animaux. Histologie et physiologie régionales |
| Résumé : |
The meeting addresses cholinergic mechanisms in central and peripheral nervous Systems, sensory organs and muscles. The development and the structure of the vertebrate neuromuscular junction are discussed, as well as its pathologies (myasthenia gravis and myasthenie syndromes). In the brain, cholinergic transmission or neuromodulation is involved in memory, sleep and arousal. Its dysfunction underlies nicotine addiction, as well as various neurological and psychiatrie disorders such as dementia and some epilepsies. The molecular genetics of cholinergic mechanisms (nicotinic and muscarinic receptors, cholinesterases, acetylcholine synthesis and release) are progressing rapidly. Cholinergic drugs are being used or evaluated for treatment of myasthenia gravis and Alzheimer's disease. Cholinergic toxicology includes poisoning by organophosphate pesticides and nerve gases, with the intriguing Persian Gulf Syndrome. The Tenth ISCM in Arcachon is an opportunity to discuss exciting new insights into fundamental aspects of cholinergic mechanisms and their conséquences for toxicology, pharmacology, medicine and the environment. This volume offers an up-to-date account of current research in the cholinergic fïeld, from the molecular level to thé most integrated levels, and its applications in toxicology and medicine. |
aspects fondamentaux et appliqués. From torpedo electric organ to human brain = De lorgane électrique de torpille au cerveau humaine : fundamental and applied aspects [texte imprimé] / Jean Massoulié, Auteur . - Elsevier, 1998 . - 523 p. ; 28 cm. ISBN : 978-2-84299-065-7 Langues : Anglais ( eng)
| Index. décimale : |
573 Les différents systèmes physiologiques des animaux. Histologie et physiologie régionales |
| Résumé : |
The meeting addresses cholinergic mechanisms in central and peripheral nervous Systems, sensory organs and muscles. The development and the structure of the vertebrate neuromuscular junction are discussed, as well as its pathologies (myasthenia gravis and myasthenie syndromes). In the brain, cholinergic transmission or neuromodulation is involved in memory, sleep and arousal. Its dysfunction underlies nicotine addiction, as well as various neurological and psychiatrie disorders such as dementia and some epilepsies. The molecular genetics of cholinergic mechanisms (nicotinic and muscarinic receptors, cholinesterases, acetylcholine synthesis and release) are progressing rapidly. Cholinergic drugs are being used or evaluated for treatment of myasthenia gravis and Alzheimer's disease. Cholinergic toxicology includes poisoning by organophosphate pesticides and nerve gases, with the intriguing Persian Gulf Syndrome. The Tenth ISCM in Arcachon is an opportunity to discuss exciting new insights into fundamental aspects of cholinergic mechanisms and their conséquences for toxicology, pharmacology, medicine and the environment. This volume offers an up-to-date account of current research in the cholinergic fïeld, from the molecular level to thé most integrated levels, and its applications in toxicology and medicine. |
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aspects fondamentaux et appliqués. From torpedo electric organ to human brain
